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Endocardial left ventricular pacing. Conduction system pacing. Multisite pacing. Multipoint pacing. Key points. Introduction. Cardiac resynchronization therapy (CRT) is an effective treatment for patients with heart failure and electrical dyssynchrony; however, despite 2 decades of clinical use, rates of nonresponse remain static at 30% to 50%. 1.
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Diastolic dysfunction occurs when the heart has a hard time relaxing between each beat. This causes restricted blood pumping and increased pressure, which leads to diastolic heart failure (also known as heart failure with preserved ejection fraction, or HFpEF ).
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