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Left ventricular ejection fraction (LVEF) is the central measure of left ventricular systolic function. LVEF is the fraction of chamber volume ejected in systole (stroke volume) in relation to the volume of the blood in the ventricle at the end of diastole (end-diastolic volume).
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When the LA contracts, LV pressure rises (LV A-wave), ending with LV end-diastolic pressure (EDP). The highest LA pressure (LAP) at end-systole is V-wave pressure. Pressure drops as the mitral valve opens. In a normal LV, early diastolic pressure gradient (blue) leads to peak early diastolic
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